The White House has warned Israel that the US will not participate in any retaliatory strikes on Iran according to senior administration officials.
Over 300 drones and missiles were fired at Israel overnight, which Iran said was in response to an April 1 strike on its consulate in Syria.
Almost all weapons were shot down by Israeli, US and allied forces before they reached their targets.
Officials said Joe Biden urged Israel to consider its response “carefully”.
Speaking to reporters on Sunday, a senior administration official said that Mr Biden told Israeli Prime Minister Benjamin Netanyahu to “think very carefully and strategically” about how his forces replied to the unprecedented action, the first direct attack by Iran on the country.
More than 80 drones and at least six ballistic missiles were downed by US aircraft and vessels or by air defence forces over Iraq.